Making materials using sometimes Substance designer and finish it in Painter or Start sculpting in Zbrush and finish texturing it in substance. its usually whatever gets me the result without spending day figuring out graphs.
Most people spend days making a sculpt. I usually spend 6hrs on my sculpt and the textures in substance designer does the rest. I used 3rocks for this wall
From A Picture to zbrush . I did a lot of sculpting but the stacking looks more convincing.